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Influence of Different Processing Methods on Content of Paeonol in Moutan Cortex

Zhengguo Li

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Abstract

Objective To investigate the influence of different processing methods on the content of paeonol in moutan cortex.Methods The RP-HPLC method was established and the DIKMa C18 column:250mm×4.6mm:5μm)was used with methanol-water(45:55)as the mobile phase.The flow rate was 1.0mL·min-1.The detection wavelength was 274nm.Results The linear range of paeonol was 0.1330～0.3102μg,r=0.9999.The average recovery was 99.18% with RSD of 0.80%(n=6).There was remarkable difference of the content of paeonol among different specifications.Conclusion The different processing methods can have remarkable influence on the content of paeonol in moutan cortex.

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What this paper is about

Objective To investigate the influence of different processing methods on the content of paeonol in moutan cortex.Methods The RP-HPLC method was established and the DIKMa C18 column:250mm×4.6mm:5μm)was used with methanol-water(45:55)as the mobile phase.The flow rate was 1.0mL·min-1.The detection wavelength was 274nm.Results The linear range of paeonol was 0.1330～0.3102μg,r=0.9999.The average recovery was 99.18% with RSD of 0.80%(n=6).There was remarkable difference of the content of paeonol among different specifications.Conclusion The different processing methods can have remarkable influence on the content of paeonol in moutan cortex.

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Available abstract

Objective To investigate the influence of different processing methods on the content of paeonol in moutan cortex.Methods The RP-HPLC method was established and the DIKMa C18 column:250mm×4.6mm:5μm)was used with methanol-water(45:55)as the mobile phase.The flow rate was 1.0mL·min-1.The detection wavelength was 274nm.Results The linear range of paeonol was 0.1330～0.3102μg,r=0.9999.The average recovery was 99.18% with RSD of 0.80%(n=6).There was remarkable difference of the content of paeonol among different specifications.Conclusion The different processing methods can have remarkable influence on the content of paeonol in moutan cortex.

Key concepts: Paeonol, Chemistry, Chromatography, High-performance liquid chromatography, Paeoniflorin, Content determination, Cortex (anatomy), Psychology

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Influence of Different Processing Methods on Content of Paeonol in Moutan Cortex — Research Paper | ScholarLens