Clinical study of treating gastric ulcer with bile reflux by hydrotalcid

Objective To investigate the clinical value of treating gastric ulcer with bile reflux by hydrotalcid. Methods Random number table method was used to divide 42 cases of gastric ulcer with bile reflux into control group and observation group, and there were 21 cases in each group. On the basis of receiving rabeprazole tablets treatment, the control group was treated with domperidone, while the observation group was treated with hydrotalcid. The clinical effect of the two groups was compared. Results After 4 weeks of treatment, there were 9 markedly effective cases, 6 effective cases and 6 ineffective cases in the control group, and the total effective rate was 71.42%(15/21). There were 15 markedly effective cases, 5 effective cases and 1 ineffective case in the observation group, and the total effective rate was 95.24%(20/21). The curative effect of the observation group was better than that of the control group. Abdominal pain, acid reflux, bloating, heartburn, nausea and other symptoms scores of the observation group were lower than the control group. The differences between two groups had statistical significance(P0.05). Conclusion Application of hydrotalcid in treating gastric ulcer with bile reflux has advantages of good curative effect and improving clinical symptoms. It is worthy of clinical learning and promotion.