Analysis of chromosomal abnormality in 500 cases of male infertility in Wenzhou

Objective:To analyze chromosomal abnormality on male infertility,and to study the relations between chromosomal abnormality and male infertility.Methods:Lymphocytes were cultured from peripheral blood of patients with male infertility,and then the chromosomes were analyzed.Results:Of 500 cases of male infertility analysed,78 cases were chromosomal abnormalities(15.6%).Sexual chromosome abnormalities were most common,34 cases of them were Klinefelter's syndrome(6.8%);32 cases were autosome abnormalities(6.4%).Conclusions:Chromosomal abnormalities,especially sexual chromosome abnormalities,are important cause of male infertility.