Adenosine triphosphate and propafenone treat paroxysmal supraventricular tachycardia in emergency room:a randomized controlled trial

Objective To evaluate the therapy effect of adenosine triphosphate and propafenone to paroxysmal supraventricular tachycardia in emergency room.Methods One hundred and seventy-three patients who were diagnosed paroxysmal supraventricular tachycardia were randomly separated into group ATP(n=86) and group propafenone(n=87).The achievement ratio,time of conversion,side effects of two drugs were compared.Results The time of conversion in group ATP and group propafenone was 0.92±0.38min and 33.00±17.00min respectively(P0.01).The achievement ratio in group ATP was 97.7% and 88.5% in group propafenone (P0.05).More mild side effects were recorded in group ATP(37.2% vs 11.5%,P0.01),whereas more severe side effects were discovered in group propafenone(4.6% vs 1.2%,P0.05).Conclusion Treat PSVT with ATP or propafenone can get a highly achievement ratio.Although ATP has more mild side effects in cardioversion,it has more safety and more successful than propafenone.