Curative effect of esmolol and propafenone on paroxysmal supraventricular tachycardia in emergency patients

Objective To analyze the curative effects of esmolol and propafenone on paroxysmal supraventricular tachycardia ( PSVT ) through comparing them. Methods The patients with PSVT ( n =120 ) were randomly divided into esmolol group and propafenone group ( each n =60 ) . On the base of treating original disease, correcting electrolyte disturbance and hypoxemia, and adjusting hydrochloric acid equilibrium in two groups, esmolol group was given injection of esmolol with infusion pump initially according to loading dose ( 0.5 mg/kg ) and adding 0.05 mg/kg at a time until showing effect, and the highest dose being 0.25 mg/kg. Propafenone group was given slow injection of 20 mL water for injection and 70 mg propafenone for 10 minutes to 15 minutes. Results The effective rate had no statistical difference between two groups ( 85.0% vs . 83.3%, P 0.05 ) , and two kinds of medicinal had similar curative effect in slowing heart rate and reducing blood pressure ( P 0.05 ) . Conclusion Esmolol has the same curative effect as propafenone in the treatment of PSVT, and esmolol is quicker and safer.