Relationship between Levels of Serum C-reactive Protein,Uric Acid and Severity of Coronary Heart Disease

Objective To explore the relationship between Levels of serum C-reactive protein(CRP),uric acid(UA)and the severity of coronary heart disease.Methods Patients undergoning coronary angiography were divided into two groups:coronary heart disease group(CHD group,n=378)and control group(n=124),the CHD group including 286 male patients and 92 female patients,which was divided into three subgroups:single-vessel disease group,double-vessel disease group and triple-vessel disease group.The levels of CRP and UA were analyzed,and then subjected to the analysis of relationship between levels of CRP,UA and severity of coronary heart disease.Results Both of CRP and UA levels in CHD group were significantly higher than those in the control group(P0.05),subgroup analysis confirmed that the patients with CHD were characterized by the higher levels of CRP and UA,the more serious of coronary artery disorder they suffered.Moreover,the levels of CRP and UA were positively correlated with the severity of CHD.Conclusion The higher level of CRP and/or UA maybe is one of risk factors for coronary heart disease.