Relationship between multiple risk factors and coronary artery lesions in the patients with coronary heart disease and metabolic syndrome

Objective To investigate the relationship between coronary artery lesions and multiple risk factors in the patients with metabolic syndrome (MS) and coronary heart disease (CHD). Methods Totally 429 patients were definitely diagnosed with CHD by coronary arteriography and their BMI, BP, FBG, TG, HDL-c as well as age, gender, smoking, TC, LDL-c, UA were recorded. All patients were divided into two groups: CHD with MS, CHD. Results BMI, BP, FBG, TG, HDL-c, TC, LDL-c and UA were significantly higher in CHD with MS group than those in CHD group (P0.05). The Gensini scores got higher and the affected vessels increased in number (P0.01) in both the two groups. Arterial stenosis was more severe in the CHD with MS group (P0.01). The coronary artery lesions were significantly correlated with HDL-c, LDL-c and BMI (P0.01). Conclusion CHD complicated with MS aggravates coronary artery lesions. HDL-c, LDL-c and BMI can serve as the predictors of CHD severity.