Evaluation of subcutaneous postoperative analgesia with lornoxicam plus fentanyl

Objective To evaluate the efficacy, safety and availability of lomoxicam plus fentanyl for subcutaneous postoperative analgesia. Methods 51 patients (ASAⅠ～Ⅱ) were randomly divided into 2 groups: Group scPCA (n=26) and Group PICA (n=25). All patients were infused loading dose of lomoxicam 8mg after the operation. Postoperative analgesia is under the fixed velocity 1ml/h. The mixture of lornoxicam plus fentanyl: lornoxicam 15μg·kg-1·h-1 plus fentanyl 0.1μg·kg-1·h-1. The VAS scores at 4, 8, 12,24,36 and 48 hours after surgery were used to evaluate the analgesic response and adverse effects. Results No significant difference between the two analgesic groups in the VAS evaluation (P0. 05 ). No significant difference of nausea and vomit between the two analgesic groups. During the period of postoperative analgesia, 4 cases were found the needle falling off, need to be intravenous injection again in group PICA, Conclusions The significant analgesia was achieved in group scPCA with lornoxicam plus fentanyl. Comparing the group PICA, group scPCA with lornoxicam plus fentanyl for postoperative analgesia is a convenient and safe methods.