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Different Routes of Administration of Iron Supplementation on Renal Anemia Efficacy and Dosage of Erythropoietin Impact Analysis

Guangquan Chen

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Abstract

Objective To different route of administration complement iron to renal anemia and the curative effect of erythropoietin dosage were investigated.Methods The 42 patients with maintenance hemodialysis patients,divided into oral iron group and intravenous iron group,respectively take oral and intravenous to complement iron,and the patients before and after treatment hematocrit(Hct),hemoglobin(Hb),transferrin saturation(TsAT) and serum ferritin(SF) level monitoring.Results Intravenous iron group Hct and Hb level much higher than oral iron group,and TAST and SF level significantly higher than before treatment,and patients with oral iron differences are statistically significant(P0.05).As the treatment the extension of time,the late oral iron group erythropoietin dosage increased,and intravenous iron group with Hb and Het leels,erythropoietin can reduce the dosage.Conclusion Intravenous application dextrose anhydride iron effect is safe,effective and renal anemia can make good improvement,to reduce the amount of erythropoietin plays an important role.

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Objective To different route of administration complement iron to renal anemia and the curative effect of erythropoietin dosage were investigated.Methods The 42 patients with maintenance hemodialysis patients,divided into oral iron group and intravenous iron group,respectively take oral and intravenous to complement iron,and the patients before and after treatment hematocrit(Hct),hemoglobin(Hb),transferrin saturation(TsAT) and serum ferritin(SF) level monitoring.Results Intravenous iron group Hct and Hb level much higher than oral iron group,and TAST and SF level significantly higher than before treatment,and patients with oral iron differences are statistically significant(P0.05).As the treatment the extension of time,the late oral iron group erythropoietin dosage increased,and intravenous iron group with Hb and Het leels,erythropoietin can reduce the dosage.Conclusion Intravenous application dextrose anhydride iron effect is safe,effective and renal anemia can make good improvement,to reduce the amount of erythropoietin plays an important role.

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Available abstract

Objective To different route of administration complement iron to renal anemia and the curative effect of erythropoietin dosage were investigated.Methods The 42 patients with maintenance hemodialysis patients,divided into oral iron group and intravenous iron group,respectively take oral and intravenous to complement iron,and the patients before and after treatment hematocrit(Hct),hemoglobin(Hb),transferrin saturation(TsAT) and serum ferritin(SF) level monitoring.Results Intravenous iron group Hct and Hb level much higher than oral iron group,and TAST and SF level significantly higher than before treatment,and patients with oral iron differences are statistically significant(P0.05).As the treatment the extension of time,the late oral iron group erythropoietin dosage increased,and intravenous iron group with Hb and Het leels,erythropoietin can reduce the dosage.Conclusion Intravenous application dextrose anhydride iron effect is safe,effective and renal anemia can make good improvement,to reduce the amount of erythropoietin plays an important role.

Key concepts: Medicine, Erythropoietin, Anemia, Transferrin saturation, Hemoglobin, Hematocrit, Internal medicine, Serum iron

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Different Routes of Administration of Iron Supplementation on Renal Anemia Efficacy and Dosage of Erythropoietin Impact Analysis — Research Paper | ScholarLens