Comparative observation of effects of intravenous iron and oral iron for hemodialysis anemia in patients

Objective To compare of treatment effects of intravenous iron and oral iron on hemodialysis ane- mia in patients with erythropoietin.Methods The oral dosage of ferrous succinate was 200mg dose,3 times a day for 2 months.After washing out for 2 months.Then these patients were given intravenous iron dextran with a dosage of 100mg twice a week for 5 weeks.During the treatment,hemoglobin (Hb),hematocrit (Hct),serum ferritin (SF) and trasferrin saturation(TSAT) were monitored.Results The efficacy of oral iron was 20 % ,the efficacy of intra- venous iron was 60 %.The Hb,Hct,SF and TSATS level increased obviously in the efficacy of intravenous iron,sta- tistical analysis showed a very significant difference(P0.01).Intravenous iron supplement was better than oral iron.Conclusion Intravenous iron might quickly improve anemia,the combination with erythropoietin had an obvi- ous therapeutic effect,which could reduce the blood transfusion and medical expenses.Intravenous iron should be se- lected firstly.