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2007•The Chinese Journal of Modern Applied PharmacyRequires access

Clinical Observation of Midodrine Hydrochloride in Preventing Hemodialysis-related Hypotension

Xiaomei Cheng

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Abstract

OBJECTIVE To observe the effect of midodrine hydrochloride to prevent hemodialysis-related hypotension and related symptoms.METHODS 37 patients(1665 hemodialysis procedures) were given midodrine hydrochloridedosage pre-,during,and post-hemodialysis,and the changes of blood pressure and clinical symptoms pre-,during,post-hemodialysis were observed. RESULTS The incidence of classic,usual,and slight symptoms were reduced significantly by using midodrine hydrochloride(P0.01).Blood pressure pre-,during,post-hemodialysis was better controlled compare to pre-medicine therapy(P0.01).CONCLUSION Midodrine hydrochloride is effective in preventing and improving clinical symptoms for the patients with hemodialysis-related hypotension.

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What this paper is about

OBJECTIVE To observe the effect of midodrine hydrochloride to prevent hemodialysis-related hypotension and related symptoms.METHODS 37 patients(1665 hemodialysis procedures) were given midodrine hydrochloridedosage pre-,during,and post-hemodialysis,and the changes of blood pressure and clinical symptoms pre-,during,post-hemodialysis were observed. RESULTS The incidence of classic,usual,and slight symptoms were reduced significantly by using midodrine hydrochloride(P0.01).Blood pressure pre-,during,post-hemodialysis was better controlled compare to pre-medicine therapy(P0.01).CONCLUSION Midodrine hydrochloride is effective in preventing and improving clinical symptoms for the patients with hemodialysis-related hypotension.

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Available abstract

OBJECTIVE To observe the effect of midodrine hydrochloride to prevent hemodialysis-related hypotension and related symptoms.METHODS 37 patients(1665 hemodialysis procedures) were given midodrine hydrochloridedosage pre-,during,and post-hemodialysis,and the changes of blood pressure and clinical symptoms pre-,during,post-hemodialysis were observed. RESULTS The incidence of classic,usual,and slight symptoms were reduced significantly by using midodrine hydrochloride(P0.01).Blood pressure pre-,during,post-hemodialysis was better controlled compare to pre-medicine therapy(P0.01).CONCLUSION Midodrine hydrochloride is effective in preventing and improving clinical symptoms for the patients with hemodialysis-related hypotension.

Key concepts: Midodrine, Hemodialysis, Medicine, Blood pressure, Anesthesia, Hydrochloride, Surgery, Internal medicine

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