The Clinical Significance of Serum Procalcitonin Levels Detected in Patients with Sepsis

Objective To study the clinical significance of PCT in patients with sepsis.Methods 100 patients with sepsis and 80 healthy volunteers were included into the study.PCT levels were studied in sepsis patients and 80 control subjects.All the patients received routine treatment,additionally treated with ulinastatin.The PCT,CRP,APACHE-Ⅱ values were detected before treatment and after treatment.The relationship between the PCT,and APACHEⅡwere studied.Results The PCT levels of Sepsis were significantly higher than control subjects(P0.01).PCT level was gradually decreasing after treatment(P0.05).The APACHE-Ⅱ values were significantly decreased after treatment(P0.05).The PCT levels was significant positive correlation with APACHE-Ⅱ(P 0.05).Conclusion PCT may has a significant predictive value on sepsis severity.