Clinical value of serum procalcitonin and C reaction protein levels detection in the patients with sepsis

Objective: To explore clinical value detecting serum procalcitonin( PCT),C reaction protein( CRP)levels in the patients with sepsis. Methods: CPT and CRP level and APACHE II scores were detected in 116 sepsis patients and compared between the survival and dead patients in different conditions. The correlation of the serum PCT,CRP levels with APACHE Ⅱ scores in patients with sepsis was analyzed,also the mortality in patients with different serum PCT levels was compared. Results: The serum PCT,CRP levels and APACHE Ⅱ scores gradually increased along with the progressing of the illness( P 0. 05); the serum PCT level was positively correlated with APACHE Ⅱ scores in patients with sepsis( r = 0. 702,P = 0. 021),the serum level of CRP had a weak positive correlation with APACHE Ⅱ scores( r = 0. 216,P = 0. 045); The serum PCT,CRP levels and APACHE Ⅱ scores of the survival patients were lower than those of the death patients( P 0. 05); the mortality increased with the increasing of serum PCT levels in patients( P 0. 05). Conclusion: Serum PCT and CRP detection has a certain clinical value in early diagnosis and prognosis of the patients with sepsis,especially,PCT can be used as an important index of serological detection in patients with sepsis.