Monitoring and analysis of drug-resistance in nosocomial infections with Pseudomonas aeruginosa.

OBJECTIVE To approach the drug-resistance of clinically isolated Pseudomonas aeruginosa(PAE) in Renmin Hospital of Jingshan County to provide the scientific accordance for the reasonable application of the antibiotics.METHODS PAE were cultured and identified according to the National Clinical Laboratory Operation Rules.Drug susceptibility testing was performed by K-B methods.RESULTS 238 strains of PAE were mainly isolated from sputum,lower respiratory tract,liquor puris,urine,blood and so on.Drug-resistance results of PAE showed that the antibiotics with the highest rate of drug sensitivity were carbopenems such as imipenem(84.5%) and meropenem(85.3%).The antibiotics whose resistance rates were more than 50% were as followed: SMZ-TMP,cefotaxime,gentamycin,ciprofloxacin,levofloxacin and aztreonam.CONCLUSION Drug-resistance status of P.aeruginosa is very serious in Renmin Hospital of Jingshan County.We should strengthen monitoring and controlling of it.