Investigation of the infection status and drug-resistance in nosocomial infections with Pseudomonas aeruginosa

Objective To investigate the infection status and drug-resistance of Pseudomonas aeruginosa(PAE) in nosocomial infections,and to provide the scientific accordance for the clinical application of the antibiotics.Methods PAE were cultured and identified according to the National Clinical Laboratory Operation Rules.The drug-sensitivity testing was performed by K-B methods.Results 109 strains of PAE were mainly isolated from the tumor(40/109,36.7%),department of internal medicine(34/109,31.2%),department of surgery(25/109,22.9%),and other department(10/109,9.2%).Drug-resistance results of PAE to 14 kinds of antibiotics showed that the antibiotics of which drug-resistance rates(44.9%-88.9%) were higher were as followed:SMZ-TMP,gentamycin,cefotaxime,cefepime,aztreonam,ciprofloxacin,levofloxacin and so on.Conclusion Drug-resistance status of Pseudomonas aeruginosa was very serious.Hospital should strengthen the monitoring,prevention and controlling of it.