2004•Liaoning zhongyi zazhiRequires access

Protective effects of the ethanolic extract from Potentilla chinensis on mice acute hepatic injury induced by carbon tetrachloride

Jia Yu-hai

Abstract

Objective:To investigate the protective effects of the ethanolic extract from Potentilla chinensis Ser.(PS) on mice acute hepatic injury induced by CCl-4.Methods:Mice were administracted with the ethanolic extract from Potentilla chinensis Ser.ig.5g·kg -1,3g·kg -1,1.8g·kg -1 daily for 7d respectively after the hepatic injury was induced by ip.10ml·kg -1 0.1% carbon tetrachloride.After 16h,serum alanine aminotransferase(ALT and AST) activity were measured,and Maleic Dialdehyde (MDA) in liver was detected.Results:The ethanolic extract from PS significantly reduce the level of serum ALT and AST,and inhabited lipoperoxidation in liver.Conclusion:Potentilla chinensis ser.showed protective effects on mice acute hepatic injury.

About this research paper

What this paper is about

Why it matters

OpenAlex reports 5 citations for this work. Citation counts describe recorded attention and do not establish research quality.

Key contribution

A contribution statement is not available in the OpenAlex record.

Method / approach

Method details are not available in the OpenAlex metadata.

Main findings

Findings are not separately available in the OpenAlex metadata.

Limitations

Limitations are not available in the OpenAlex metadata.

Applications

Application details are not available in the OpenAlex metadata.

Available abstract

Key concepts: Carbon tetrachloride, Medicine, Traditional medicine, Potentilla, CCL4, Alanine aminotransferase, Liver injury, Pharmacology