2011•Zhejiang Journal of Integrated Traditional Chinese and Western MedicineRequires access

Effects of Rosiglitazone on Renal Pathological Changes in Diabetic Rats

Pang Yupin

Abstract

Objective: To investigate patho-alteration of kidney in diabetic nephropathy rats treated with rosiglitazone.Methods: Thirty Sprague-Dawley male rats were randomized into normal control,diabetic,and rosiglitazone-treating groups,10 in each.Rosiglitazone was given at the dose of 1 mg/kg/d to the rosiglitazone-treating group.Pathological changes in the kidney of diabetic rats before and after intervention were observed.Results: The pathological changes of the rosiglitazones-treating group were milder than that in the diabetic group.Conclusion: Rosiglitazones may improve patho-alteration in the kidney of diabetic rats.

About this research paper

What this paper is about

Why it matters

A significance statement is not available in the OpenAlex record.

Key contribution

A contribution statement is not available in the OpenAlex record.

Method / approach

Method details are not available in the OpenAlex metadata.

Main findings

Findings are not separately available in the OpenAlex metadata.

Limitations

Limitations are not available in the OpenAlex metadata.

Applications

Application details are not available in the OpenAlex metadata.

Available abstract

Key concepts: Rosiglitazone, Medicine, Diabetic nephropathy, Pathological, Kidney, Internal medicine, Diabetes mellitus, Endocrinology