The Influence of Salmeterol Fluticasone Joint with Montelukast on the IL-4 INF-γ Ig E EOS of Asthmatic Children

Objective: To investigate the clinical efficacy and immune function of salmeterol fluticasone joint with montelukast on asthmatic children. Method: From January 2011 to December 2013,102 cases of asthmatic children were divided into test group and control group according to different treatment methods,each had 51 cases. The control group accepted salmeterol fluticasone inhalants,while the test group accepted montelukast on the basis of control group. Result: The total effective rate of test group was 96. 1%,while the control group was 82. 4%,the difference was statistically significant( P 0. 05). The difference was not statistically significant on compliance rates of lung function between the two groups before the treatment( P 0.05). But at he treatment of 3 months and after 3 months,the compliance rates of lung function of text group were all better than the control group( P 0. 05). The difference was not statistically significant on IL-4,INF-γ,Ig E,EOS between the two groups before the treatment( P 0. 05). But at he treatment of 3 months and after 3 months,the levels of IL-4,Ig E and EOS of two groups were all lower than before,and the levels of the INF-γ was higher than before( P 0. 05). The difference was statistically significant between the two groups( P0. 05). Conclusion: The treatment of salmeterol fluticasone joint with montelukast on asthmatic children have significant effect,good safety. It is worthy of being popularizing on clinical.