ANALYSIS OF USING SALMETEROL XINAFOATE COMBINED WITH FLUTICASONE PROPIONATE MONTELUKAST TO TREAT MODERATE ASTHMA IN CHILDREN

Objective To investigate the therapeutic effects of administration of salmeterol and fluticasone inhalant alone with respect to its combination with montelukast to children asthma. Methods Fifty asthmatic children were divided randomly into two groups, the treatment group subjected to salmeterol and fluticasone inhalant plus montelukast, and the control group to salmeterol and fluticasone inhalant alone. The peak expiratory flow rate (PEFR) value and symptom during the day and at night were evaluated after treatment for 12 weeks. Result Compared with the control group, the number of PEFR in the treatment group were improved significantly after 12 weeks of treatment (p0.05).,and the clinic scores in the treatment group were significantly lower than that in the control group (p0.01) Conclusion The clinical symptoms and lung function were significantly improved in the group treated with salmeterol and fluticasone inhalant in combination with montelukast as compare to the other treated with salmeterol and fluticasone inhalant alone.