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2007•Journal of Hubei Institute for NationalitiesRequires access

A Study on Extracting and Determining Magnolol and Honokiol in Huoxiang Zhengqi Troche

Xiaopeng Liu

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Abstract

Objective:to establish and improve a method for quick extraction and determination of Magnolol and Honokiol.Methods:Magnolol and Honokiol were quickly extracted on ASE300 system.Magnolol and Honokiol were separated on Diamonsil(TM)C18 column(250mm×4.6 mm,5μm) and detected at 294 nm,using methanol-water-acetic acid glacial(79∶21∶0.25) as mobile phase.Results:The standard curves for Magnolol and Honokiol were linear in the range of 6.25～400 μg/mL.The average recoveries of Magnolol and Honokiol were 99.88%(RSD=1.25%) and 100.27%(RSD=1.38%) respectively.Conclusions:The method is simple,rapid and accurate and it can effectively control the quality of Huoxiang Zhengqi troche.

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What this paper is about

Objective:to establish and improve a method for quick extraction and determination of Magnolol and Honokiol.Methods:Magnolol and Honokiol were quickly extracted on ASE300 system.Magnolol and Honokiol were separated on Diamonsil(TM)C18 column(250mm×4.6 mm,5μm) and detected at 294 nm,using methanol-water-acetic acid glacial(79∶21∶0.25) as mobile phase.Results:The standard curves for Magnolol and Honokiol were linear in the range of 6.25～400 μg/mL.The average recoveries of Magnolol and Honokiol were 99.88%(RSD=1.25%) and 100.27%(RSD=1.38%) respectively.Conclusions:The method is simple,rapid and accurate and it can effectively control the quality of Huoxiang Zhengqi troche.

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Available abstract

Objective:to establish and improve a method for quick extraction and determination of Magnolol and Honokiol.Methods:Magnolol and Honokiol were quickly extracted on ASE300 system.Magnolol and Honokiol were separated on Diamonsil(TM)C18 column(250mm×4.6 mm,5μm) and detected at 294 nm,using methanol-water-acetic acid glacial(79∶21∶0.25) as mobile phase.Results:The standard curves for Magnolol and Honokiol were linear in the range of 6.25～400 μg/mL.The average recoveries of Magnolol and Honokiol were 99.88%(RSD=1.25%) and 100.27%(RSD=1.38%) respectively.Conclusions:The method is simple,rapid and accurate and it can effectively control the quality of Huoxiang Zhengqi troche.

Key concepts: Magnolol, Honokiol, Chromatography, Chemistry

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