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2007•Qilu Pharmaceutical AffairsRequires access

Determination of Magnolol and Honokiol in Huoxiang Zhengqi Capsule by HPLC

Wang Guoping

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Abstract

OBJECTIVE To set up a method for determination of magnolol and honokiol in Huoxiang Zhengqi capsule.METHODS HPLC method was adopted.The mobile phase was methanol-water(75∶25),the flow rate was 1.0ml·min-1,and the UV detection wavelength was 294nm.RESULTS Average recovery rate of magnolol was 99.81%,RSD was 0.3%(n=5);average recovery rate of honokiol was 100.14%,RSD was 0.8%(n=5).CONCLUSION The method is simple,accurate and suitable for the assay of magnolol and honokiol in Huoxiang Zhengqi capsule.

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What this paper is about

OBJECTIVE To set up a method for determination of magnolol and honokiol in Huoxiang Zhengqi capsule.METHODS HPLC method was adopted.The mobile phase was methanol-water(75∶25),the flow rate was 1.0ml·min-1,and the UV detection wavelength was 294nm.RESULTS Average recovery rate of magnolol was 99.81%,RSD was 0.3%(n=5);average recovery rate of honokiol was 100.14%,RSD was 0.8%(n=5).CONCLUSION The method is simple,accurate and suitable for the assay of magnolol and honokiol in Huoxiang Zhengqi capsule.

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Available abstract

OBJECTIVE To set up a method for determination of magnolol and honokiol in Huoxiang Zhengqi capsule.METHODS HPLC method was adopted.The mobile phase was methanol-water(75∶25),the flow rate was 1.0ml·min-1,and the UV detection wavelength was 294nm.RESULTS Average recovery rate of magnolol was 99.81%,RSD was 0.3%(n=5);average recovery rate of honokiol was 100.14%,RSD was 0.8%(n=5).CONCLUSION The method is simple,accurate and suitable for the assay of magnolol and honokiol in Huoxiang Zhengqi capsule.

Key concepts: Magnolol, Honokiol, Capsule, Chromatography, Chemistry, High-performance liquid chromatography, Botany, Biology

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