Outcomes of terminating medium-term pregnancy with rivanol combined use of mifepristone and misoprostol

Objective To observe the clinical outcomes of terminating medium-term pregnancy with rivanol combined use of mifepristone and misoprostol.Methods Seventy-six wemem with 16 to 27 weeks pregnancy who asked medium-term termination were divided into two groups.The patients in group A(40 cases) were injected rivanol 100 mg into amniotic cavity,which was followed by oral mifepristone 75 mg twice within 12 h and misoprostol 600 g put into the anus.The patients in group B(36 cases) were injected rivanol 100 mg into amniotic cavity only as the controls for induced abotion.Cervical Bisshop scores,placenta delivery time,amount of bleeding were recorded and compared between two groups.Results Success rate of abortion of two groups was 100%.Compared to group B,the cervical Bisshop score in group A was increased[(3.9±1.0) points vs.(6.1±1.1) points](P0.01),but placenta delivery time[(30.3±2.9) h vs.(23.4±2.6) h] and amount of bleeding[(80.5±32.7) ml vs.(20.1±26.3) ml] were all significantly less (P0.01).Conclusion Terminating medium-term pregnancy with rivanol combined use of mifepristone and misoprostol is effective and safe with the advantages of simple use,less hospital stay and expense.