Analysis of the Drug Resistance and Distribution and of 107 Strains of Pathogenic Bacteria in Blood Culture Specimens

Objective To investigate the distribution and drug-resistance of bacteria in septicemia or bacteremia, and to provide the experimental evidence for clinical therapy. Methods The clinical specimens were collected in recent 4 years. Identification of the bacteria and antimicrobial susceptibility test were performed on all-automatic microbiology analysis system. Results 706 blood cultures were detected from Jan 2007 to Dec 2010. Of 107 cases with positive culture(15%) including 68 Gram-positive bacteria strains(63.6%), 36 Gram-negative bacteria strains(33.6%), 3 Candida strains(2.8%). The drug susceptive results showed that Gram-positive bacteria were sensitive to Meropemen and Imipenem severely, while Gram-negative bacteria were sensitive to Minocycline, Vancomycin, Van, Teieoplanin, TEC. Conclusion Gram-negative bacteria are the main stains in blood culture. The rate of the drug resistance of some bacteria is high, which indicates that it is necessary to analyze the resistance of pathogens and its distribution regularly.