Distribution and Analysis of Resistance of Pathogens in Blood Culture

Objective To investigate the distribution and bacterial resistance of clinical isolates from the blood culture in recent 3 years for the guidance of rational use of antibiotics.Methods BacT/Alert 120 was used for blood culture and the isolated bacteria were identified by API identified tests(API Inc,France).Antibiotics sensitivity test was performed by Kirby-Bauer(K-B).Results Of 1 111 cases with positive culture including 361 Gram-positive bacteria strains(32.5%),510 Gram-negative bacteria strains(45.9%),162 Candida strains(14.6%).The drug susceptive results showed that Gram-positive bacteria were resistant to penicillin severely,while Gram-negative bacteria were sensitive to Carbapenems,and Candida were still sensitive to some antibiotics.Conclusion Gram-negative bacteria were the main stains in blood culture in XX hospital,and they were diverse.The rate of the drug resistance of some bacteria was high,which indicated that it was necessary to analyze the resistance of pathogens and its distribution regularly.