Drug Resistant and Distribution of Bacteria Isolated from Blood Culture from 2011 to 2012 in the Hospital

Objective To investigate the changes of bacterial spectra and drug resistance of pathogenic bacteria in blood culture,and provide a basis for clinical treatment.Methods Blood was cultured by Bactec 9120 of BD.The clinical isolates were identified by VETEK-Ⅱand phoenix-100 of BD.The results was analyzed by WHONET5.4.Results 898 strains of pathogenic bacteria were isolated from 8 040 clinic blood specimens,of which Escherichia coli(164 strains,18.3%),Staphylococcus epidermidis(112 strains,12.5%) and Klebsiella pneumoniae(83strains,9.2%) are most familiar.The sensitivity of Gram-negative bacteria to imipenem was the highest;the sensitivity of Gram positive bacteria to teicoplanin and vancomycin were the highest.Conclusion Gram-negative bacteria are the main stains in blood culture in the hospital,and they are diverse.The rate of the drug resistance of some bacteria is high,which indicated that it is necessary to analyze the resistance of pathogens and its distribution regularly.Monitoring the changes of pathogens and trends of drug resistance is very important in guiding the clinical use of antibiotics.