Clinical study on changes in serum nitric oxide content in different periods of cerebral hemorrhage

Objective To study the clinical significance of changes in serum nitric oxide content in different periods of cerebral hemorrhage.Methods Modified Green's method was used to measure serum NO content in 38 cerebral hemorrhage patients and 30 subjects were tested as the normal control group.Results The average serum concentrations of NO in different periods of cerebral hemorrhage were lower than those in the control group,while the serum NO concentration in 24 hour group was significantly higher than that in other groups and control group.The degree of cerebral hemorrhage was negatively correlated with NO content in serum and the NO contents were different in various regions of cerebral hemorrhage.Conclusion NO is involved in the pathophysiology of cerebral hemorrhage.This provides theoretical basis for managing cerebral hemorrhage in clinical practice.