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Comparison of HBV Serum Marker between TRFIA and ELISA

Lin Yongting

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Abstract

Objective To explore the clinical value and relationship between time-resolved fluoro immunoassay (TRFIA) to detect HBV-M in quantity and enzyme linked immunosorbent assay (ELISA) to detect HBV-M in quality. Methods 436 serum specimen were collected to detect HBV-M by TRFIA and ELISA. Results The positive results of TRFIA were higher than thoset of ELISA for nearly cut-off value HBV-M specimen. Conclusions TRFIA is more sensitive than ELISA. It can provide the dynamic data for diagnosis and the curativ effect observation of hepatitis B, which is a perfect quantiative method.

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What this paper is about

Objective To explore the clinical value and relationship between time-resolved fluoro immunoassay (TRFIA) to detect HBV-M in quantity and enzyme linked immunosorbent assay (ELISA) to detect HBV-M in quality. Methods 436 serum specimen were collected to detect HBV-M by TRFIA and ELISA. Results The positive results of TRFIA were higher than thoset of ELISA for nearly cut-off value HBV-M specimen. Conclusions TRFIA is more sensitive than ELISA. It can provide the dynamic data for diagnosis and the curativ effect observation of hepatitis B, which is a perfect quantiative method.

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Available abstract

Objective To explore the clinical value and relationship between time-resolved fluoro immunoassay (TRFIA) to detect HBV-M in quantity and enzyme linked immunosorbent assay (ELISA) to detect HBV-M in quality. Methods 436 serum specimen were collected to detect HBV-M by TRFIA and ELISA. Results The positive results of TRFIA were higher than thoset of ELISA for nearly cut-off value HBV-M specimen. Conclusions TRFIA is more sensitive than ELISA. It can provide the dynamic data for diagnosis and the curativ effect observation of hepatitis B, which is a perfect quantiative method.

Key concepts: Medicine, HBsAg, Immunoassay, Hepatitis B virus, Immunology, Virology, Internal medicine, Gastroenterology

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