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2010•Zhongguo quanke yixueRequires access

Relationship between Plasma IL-10 Level and T2DM Macrovascular Complications

Hu Qiu

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Abstract

Objective To investigate the relationship between plasma IL-10 levels and T2DM macrovascular complications.Methods A total of 84 T2DM patients were enrolled,including 50 with macrovascular lesions (group A) and 34 without (group B).Anther 50 healthy subjects were chosen as control group.Serum IL-10 levels were detected by ELISA kits in 3 groups.Results The levels of serum IL-10 were lower in group A than in control (2 . 7±0 . 9 ng/L,4 . 5±1 . 6 ng/L,respectively),the difference was significant (P0 . 05).There was not significant difference in IL-10 levels between groups B and control(P0.05).Conclusion Low-IL-10 hyperlipidemia exists in T2DM patients with macrovascular lesions,suggesting that inflammation is involved in the occurrence and development of T2DM macrovascular complications.IL-10 may be one of the risk factors and predictors of T2DM macrovascular lesions.

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What this paper is about

Objective To investigate the relationship between plasma IL-10 levels and T2DM macrovascular complications.Methods A total of 84 T2DM patients were enrolled,including 50 with macrovascular lesions (group A) and 34 without (group B).Anther 50 healthy subjects were chosen as control group.Serum IL-10 levels were detected by ELISA kits in 3 groups.Results The levels of serum IL-10 were lower in group A than in control (2 . 7±0 . 9 ng/L,4 . 5±1 . 6 ng/L,respectively),the difference was significant (P0 . 05).There was not significant difference in IL-10 levels between groups B and control(P0.05).Conclusion Low-IL-10 hyperlipidemia exists in T2DM patients with macrovascular lesions,suggesting that inflammation is involved in the occurrence and development of T2DM macrovascular complications.IL-10 may be one of the risk factors and predictors of T2DM macrovascular lesions.

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Available abstract

Objective To investigate the relationship between plasma IL-10 levels and T2DM macrovascular complications.Methods A total of 84 T2DM patients were enrolled,including 50 with macrovascular lesions (group A) and 34 without (group B).Anther 50 healthy subjects were chosen as control group.Serum IL-10 levels were detected by ELISA kits in 3 groups.Results The levels of serum IL-10 were lower in group A than in control (2 . 7±0 . 9 ng/L,4 . 5±1 . 6 ng/L,respectively),the difference was significant (P0 . 05).There was not significant difference in IL-10 levels between groups B and control(P0.05).Conclusion Low-IL-10 hyperlipidemia exists in T2DM patients with macrovascular lesions,suggesting that inflammation is involved in the occurrence and development of T2DM macrovascular complications.IL-10 may be one of the risk factors and predictors of T2DM macrovascular lesions.

Key concepts: Medicine, Internal medicine, Hyperlipidemia, Significant difference, Gastroenterology, Inflammatory response, Inflammation, Endocrinology

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