Curative Effect of Amlodipine Combined with Irbesartan in Treatment of 47 Cases of Primary Hypertension

Objectives To discuss the curative effect of amlodipine combined with irbesartan in treatment of primary hypertension.Methods We selected the primary hypertension patients who were treated at our hospital from May 2010 to April 2012,divided them into amlodipine group(14 cases),irbesartan group(16 cases) and drug combination group(17 cases) according to random number table,and adopted amlodipine,irbesartan,and combination of amlodipine and irbesartan to treat these patients in three groups,respectively.The curative effects after treatment were observed and analyzed statistically.Results The target rate in drug combination group was 29.8% and 37.8% higher than amlodipine group and irbesartan group,respectively(P0.05).There were no significant differences in the systolic pressure and diastolic pressure before treatment among patients in the three groups(P0.05),and there were significant differences after treatment among patients in the three groups(P 0.05).Conclusion Both amlodipine and irbesartan have good curative effect in the treatment primary hypertension,but combination of these two has better effect.