Clinical Observation of Cetaphil Lotion in Adjuvant Treatment of Infantile Eczema

Objective To evaluate the efficacy and safety of triamcinolone acetonide and econazole nitrate cream (Pevisone ) combined with Cetaphil lotion in treatment of infantile xerotic eczema. Methods A randomized controlled open trial was performed. The combined group was applied with Pevisone cream and Cetaphil lotion twice per day alternatively, and the later was maintained after the rash cured. The Pevisone group was treated with triamcinolone acetonide and econazole nitrate cream twice per day only and the therapy was switched to once every day after the rash disappeared. The Cetaphil group was treated with Cetaphil lotion twice per day only.The variations of the rash were recorded and the total scores of erythema, papule,scale, pruritus and area were evaluated in the return visit of the same day visiting 1,2weeks after medication and a week after recovery. Results The obvious effective rate with 65.00% and cure rate with 46.25% of the combined group were significantly higher than those in Cetaphil group after 1 weeks of therapy, which with 90.00% and 68.75% were higher than both control groups after 2 weeks of therapy.But there was no statistical difference between the two control groups as to the obvious effective rate and the cure rate. Conclusion Cetaphil lotion has a better adjuvant therapeutic effect on xerotic eczema in infants and itching of the skin lesions. It was of a certain spreading value in clinical.