Clinical observation of Desonide cream combined with Triple emollient cream in treatment of infantile xerotic eczema in face

Objective To evaluate the efficacy and safety of 0.05% Desonide cream combined with Triple emollient cream in treatment of infantile xerotic eczema in face in autumn and winter. Methods A randomized controlled open trial was performed. The treatment group was applied with desonide cream and triple emollient cream twice per day alternatively, and the later was maintained after the rash cured. The control group was treated with 0.05% desonide cream twice per day only and the therapy was switched to once every day for three days after the rash cured. The variations of the rash were recorded and the total scores of erythema, papule ,scale and pruritus were evaluated in the return visit of the same day visiting ,3,5,7,10days after medication and 7 days after recovery. Results The obvious effective rate of treatment group was significantly higher than control group on 3,5,7 day of therapy and equivalent on 10 day. The cure rate of treatment group was higher than control group on 7 day after recovery. Conclusions Triple moisture cream has a better adjuvant therapeutic effect on facial xerotic eczema in infants and itching of the skin lesions. It was of a certain spreading value in clinical.