Clinical observation of rabeprazole,levofloxacin and amoxicillin triple therapy on peptic ulcer

Objective To explore the efficacy and security of rabeprazole,levofloxacin and amoxicillin triple therapy in the treatment of peptic ulcer.Methods Selected 120 cases peptic ulcer patients diagnosed in our hospital from June 2011 to January 2012 as the observation objects,all patients according to the random number table were divided into treatment group(rabeprazole,levofloxacin and amoxicillin triple therapy) and control group(omeprazole,clarithromycin and amoxicillin triple therapy) with 60 cases,and the clinical efficacy of Hp eradication rate of two groups were compared.Results All patients successfully completed the entire course of treatment,the total effective rate of the control group was 78.3%,was significantly lower than the treatment group(96.6%),and the difference was statistically significant(χ2 = 7.824,P = 0.003 16).Hp eradication rate of the observation group was 93.3%(56/60),Hp eradication rate of control group was 70.0%(42/60),and the difference was statistically significant(P 0.05).Conclusion Rabeprazole,levofloxacin and amoxicillin triple therapy in the treatment of peptic ulcer is a significant eradication of Helicobacter pylori significantly,security,and worthy of promotion and application.