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2008•Journal of clinical surgeryRequires access

Relation of UPA and CD34 to invasion and metastasis of gastric cancer and their relativity

Qian Wang

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Abstract

Objective To study the relationship between UPA and CD34 with invasion and metastasis of gastric cancer and their relativity.Methods Immunohistochemical staining for UPA and CD34 was performed with a standard avidin-biotin-peroxidase complex detection kit.Results The expression of UPA and CD34 was up-regulated in gastric cancer and obviously increased with the decrease of differentiation,lymphatic metastasis,long distance metastasis,increase of clinical stage.In gastric cancer there was a positive relativity between the UPA and CD34 expression.Conclusion UPA and CD34 play an important role in promoting the pathogenesis of gastric cancer,invasion and metastasis.UPA and CD34 have a close interaction.

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What this paper is about

Objective To study the relationship between UPA and CD34 with invasion and metastasis of gastric cancer and their relativity.Methods Immunohistochemical staining for UPA and CD34 was performed with a standard avidin-biotin-peroxidase complex detection kit.Results The expression of UPA and CD34 was up-regulated in gastric cancer and obviously increased with the decrease of differentiation,lymphatic metastasis,long distance metastasis,increase of clinical stage.In gastric cancer there was a positive relativity between the UPA and CD34 expression.Conclusion UPA and CD34 play an important role in promoting the pathogenesis of gastric cancer,invasion and metastasis.UPA and CD34 have a close interaction.

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Available abstract

Objective To study the relationship between UPA and CD34 with invasion and metastasis of gastric cancer and their relativity.Methods Immunohistochemical staining for UPA and CD34 was performed with a standard avidin-biotin-peroxidase complex detection kit.Results The expression of UPA and CD34 was up-regulated in gastric cancer and obviously increased with the decrease of differentiation,lymphatic metastasis,long distance metastasis,increase of clinical stage.In gastric cancer there was a positive relativity between the UPA and CD34 expression.Conclusion UPA and CD34 play an important role in promoting the pathogenesis of gastric cancer,invasion and metastasis.UPA and CD34 have a close interaction.

Key concepts: Metastasis, CD34, Cancer, Immunohistochemistry, Pathology, Distant metastasis, Cancer research, Medicine

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