2007•Zhongguo jiceng yiyaoRequires access

Approach of clinical significance of serum C-reactive protein levels in acute coronary syndrome patients

HU Zong-chang

Abstract

Objective To observe changes of serum levels of soluble C-reactive protein(CRP)in patients with acute coronary syndrome.Methods The levels of CRP were measured in 46 patients with ACS,31 patients with SAP and 30 controls.Seventy-seven patients with coronary angiography were divided into three types according to the morphological division of the plaque:type Ⅰ,type Ⅱand type Ⅲ.Results The levels of CRP in ACS group were significantly higher than those in SAP group and control group(P0.01).The levels of CRP of type Ⅱ were significantly higher than those in type Ⅰ and type Ⅲ(P0.01).Conclusion Elevation of serum level of CRP is related with unstable plaque.It can be used as a serum target to judge plaque rupture.

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Key concepts: Medicine, C-reactive protein, Internal medicine, Acute coronary syndrome, Gastroenterology, Coronary angiography, Cardiology, Inflammation