Clinical function of plasma homocysteine test in patients with cerebral infarction

Objective To investigate the clinical function of plasma homocysteine(Hcy) test in patients with cerebral infarction. Methods A total of 130 patients with cerebral infarction admitted to the department of neurology were selected as clinical test group, while 130 healthy people who underwent physical examination were selected as normal control group. Blood(5 ml) was collected from each person via the cubital vein after 12 h of fasting in the second day of hospitalization. Fluorescence polarization immunoassay was adopted for Hcy measurement. Results The clinical test group had significantly higher incidence of high Hcy and Hcy level than the normal control group(P 0.05). The clinical test group showed significantly decreased Hcy level after treatment(P 0.05). With the worsening of the condition, Hcy level and neurological deficit scores would increase accordingly. There were significant differences between subgroups(severe cerebral stroke, moderate cerebral stroke, and mild cerebral stroke)(P0.05). Conclusion The Hcy level in patients with cerebral infarction is significantly higher than that in healthy people. The severity of cerebral infarction is proportional to Hcy level, which can be remarkably decreased by effective therapy. Hcy level, which is of great importance, is a reference index for curative effect observation and clinical diagnosis.