Clinical analysis of 58 cases of luteinized unruptured follicle syndrome

Objective To evaluate the treatment of luteinized unruptured follicle syndrome(LUFS) in patients with polycystic ovary syndrome(PCOS) in ovulation induction.Methods Fifty-eight LUFS patients with PCOS in ovulation induction were analyzed.All patients were divided into two groups.35 cases (Group 1) were underwent ultrasound-directed follicular aspirations and 23 cases(Group 2) were give gynecological examination with mechanical extruding.Results All 35 cases in group 1 were successful in ovulation induction.Eleven pregnancies and one moderate ovarian hyperstimulation syndrome(OHSS) occurred in group 1,resulting in a pregnancy rate of 31.4%,and an incidence of moderate OHSS 2.9%.Two pregnancies and 11 ovulation induction developed in group 2 with 3 moderate OHSS,resulting in a pregnancy rate of 8.7%,an incidence of ovulation 47.8%,and an incidence of moderate OHSS 13.0%.No severe cases of OHSS were noted in either of the two groups.Comparison of the therapeutic effects between the two groups showed significant difference(P0.001),with higher incidence of ovulation in group 1 than in group 2.No significant differences were noted in pregnancy rate and incidence of moderate OHSS(P0.05 ).Conclusion The therapy of ultrasound-directed follicular aspirations is effective in treating LUFS with PCOS in ovulation induction.