Treatment of polycystic ovar ian syndrome with anovulatory infertility by immature follicle aspiration

Objective:To investigate the effect of ultrasound-guided immature follicle aspiration on polycystic ovarian syndrome(PCOS) in women with anovulatory infertility.Methods: 47 PCOS patients were involved in this trial,and divided into 2 groups.Group Ⅰ were administered with gonadotropin(Gn),and were asked to undergo ultrasound-guided follicular aspiration after the diameter of the advan-tage occyte more than 12mm.Only one or two follicles for every ovary were remained and Gn administration was continued.In Group Ⅱ,20 patients of did not use Gn,but recepted aspiration,but were administered with Gn in the next cycle.ovulation rate,pregnancy rate,twins rate and OHSS rate were monitored.Results: In Group I,the ovulation rate was 88.9%,the pregnancy rate was 37.0%,twins rate was 20%,no patients developed ovarian hyperstimulation sydrome(OHSS).In Group 2,the ovulation rate was75.0%,the pregnancy rate was 30.0%,twins rate was 5%,Only 2patients developed OHSS.The were significant differences in the rate of ovulation and twins and OHSS.Conclusions: Immature follicle aspiration treatment can achieve pregnancy I with Gn administration,meanwhile,avoid OHSS in clomiphen citrate-resistant PCOS patients.