2012•Zhongguo xiandai yixue/Zhongguo xiandai yixue zazhiRequires access
Discussion of the relationship between E-selectin and ICAM-1with acute coronary syndrome
Yunli Zhang
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Abstract
【Objective】To explore the difference of E-selectin and intercellular adhesion molecule-1(ICAM-1) in different type of acute coronary syndrome(ACS) and the associated correlations between E-selectin and ICAM1with ACS.【Methods】197 patients who were divided into three groups: stable effort angina group(SAP)(n =62),acute coronary syndrome group(ACS)(n =90),control group(n =45).The serum levels of E-selectin and ICAM-1 were detected by ELISA,and the relationship between E-selectin and ICAM-1 were analyzed.【Results】The serum levels of E-selectin and ICAM-1 in ACS group were significantly higher than those in SAP and control group(P 0.01),and the serum levels of ICAM-1 between SAP and control group were different(P 0.01).There was positive correlation between E-selectin and ICAM-1 in ACS(P 0.05).【Conclusion】The serum levels of E-selectin and ICAM-1 are important index for the diagnosis of ACS and the severity of ACS.