Study on formation technology of baicalin dropping pills

Aim To optimize the best technical parameters through controlling the different factors.Methods Dissolution,appearance and weight coefficient of variation were used as comprehensive evaluation indicators to select good prescriptions and dropping conditions.Results The optimized preparation conditions were as follows:with PEG4000 as optimal bases,optimal drugs and bases is 1∶2,temperature of mixture is 90℃,dropping speed is 45 drop ·min-1,5℃ dimethylsilicone oil is condensate,and dropping distance is 6 cm.Conclusions The preparation procedure is simple,feasible,stable and reproducible.