2008•Strait Pharmaceutical JournalRequires access

Study on preparation technology of Radix isatidis dropping pills

Sanbao Chen

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Abstract

OBJECTIVE To optimize the best technical parameters through controlling the different factors.METHODS Dissolution,appearance and weight variation was used as comprehensive evaluation indicator to select good prescriptions and dropping conditions.RESULTS The optimized preparation conditions were as follows:PEG4000+PEG6000(1∶9) was optimal bases,optimal drugs and bases was 1∶2,temperature of mixture was 90℃,dropping speed was 45 drop/min,5℃ dimethylsilicone oil was condensate,dropping distance was 6cm.CONCLUSION The preparation procedure is simple,feasible,the grade point index sign is credibility and reasonable.

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What this paper is about

OBJECTIVE To optimize the best technical parameters through controlling the different factors.METHODS Dissolution,appearance and weight variation was used as comprehensive evaluation indicator to select good prescriptions and dropping conditions.RESULTS The optimized preparation conditions were as follows:PEG4000+PEG6000(1∶9) was optimal bases,optimal drugs and bases was 1∶2,temperature of mixture was 90℃,dropping speed was 45 drop/min,5℃ dimethylsilicone oil was condensate,dropping distance was 6cm.CONCLUSION The preparation procedure is simple,feasible,the grade point index sign is credibility and reasonable.

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Available abstract

OBJECTIVE To optimize the best technical parameters through controlling the different factors.METHODS Dissolution,appearance and weight variation was used as comprehensive evaluation indicator to select good prescriptions and dropping conditions.RESULTS The optimized preparation conditions were as follows:PEG4000+PEG6000(1∶9) was optimal bases,optimal drugs and bases was 1∶2,temperature of mixture was 90℃,dropping speed was 45 drop/min,5℃ dimethylsilicone oil was condensate,dropping distance was 6cm.CONCLUSION The preparation procedure is simple,feasible,the grade point index sign is credibility and reasonable.

Key concepts: Radix (gastropod), Chromatography, Mathematics, Process engineering, Computer science, Chemistry, Engineering, Botany

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