Clinical observation of Salvia Miltiorrhiza and Ligustrazine injection in obliterans

Objective To analyze the effect of salvia miltiorrhiza and ligusrtazine injection solution in the treatment of patients with obliterans. Methods A data of 56 patients with obliterans were randomly divided into the control group(28patients) and the treatment group(28patients) . The control group was treated with low molecular dextran,while the treatment group was given salvia miltiorrhiza and ligustrazine injection in addition. The total period of treatment was 1 month. D-dimer and Hemorheology indexes were determined . Variations were assessed before and after the treatment,besides,efficacy was evaluated . Results The herapeutic effect was much better in the treatment group compared with the control group(P 0.05). The levels of D-dimer decreased significantly(P 0.05) in the treatments and more those of control of control group. Hematocrit data in treatment group was decreased compared with those before treatment. Besides,compared with control group, low-shear viscosity,plasma viscosity and fibrinogen reduced significantly( P 0. 05). Conclusion Salvia miltiorrhiza and ligustrazine injection can effectively ameliorate the hemorheological indes and D-dimer,is effective for the treatment of obliterans.