An Efficacy Comparison Study of Intravenous Diltiazem versus Nitroglycerol in Treating Acute Hypertension

Objective To evaluate the efficacy of intravenous diltiazem versus nitroglycerol in treating acute hypertension.Methods A random study including 90 patients with acute hypertension was conducted to evaluate the efficacy of intravenous diltiazem versus nitroglycerol,of which 50 patients were treated with diltiazem and 40 patients were treated with nitroglycerin in intravenous drip,respectively.The curative effects of two groups were compared by monitoring the changes in heart rate and blood pressure,recording heart rate(HR),systolic blood pressure(SBP) and diastolic blood pressure(DBP) before and after administration,calculating rate-pressure product(RPP) and the tim(eT) needed for blood pressure decreasing to the normal range.Results Compared with the patients treated with nitroglycerin(80%),the total effective rate was better for patients treated with diltiazem(100%),P0.05.Moreover,the myocardial oxygen consumption and side effect of patients treated with diltiazem were both lower than that of patients treated with nitroglycerin.Conclusion The efficacy of intravenous diltiazem in treating acute hypertension is better and safer than that of intravenous nitroglycerin.