ScholarLens Back to search
2005•Shiyong laonian yixueRequires access

The effects of intravenous diltiazem for aged patients with hypertension crisis

Lin Hon

Open publisher page 0 citations

Abstract

Objective To evaluate the effects of intravenous diltiazem for aged patients with hypertension crisis. Methods Intravenous diltiazem was given to group A(n=30, SBP 192.4±17.2mmHg and DBP 110.6±8.8 mmHg) 10-20 mg, and intravenous nitroglycerin was given to group B(n=31, SBP 189.7±16.9 mmHg and DBP 112.8± 7.4 mmHg) 10 mg within 2 hours. The blood pressure (BP) was observed after 5 min, doses recorded and regulated according to BP, ECG, HR, SBP, DBP, HR×SBP and tolerance dosage. Results After treatment with diltiazem and nitroglycerin the BP of all patients decreased significantly(P0.01). More adverse events like headache(8 patients), dizziness, swelling, palpitation(6 patients) developed and 3 patients could not tolerate in group B. ST-T, in ECG improved in 2 groups but there was no statistical significance. None suffered from A-VB, severe low BP and heart failure. Conclusions The intravenous diltiazem is more effective and safer to treat aged patients with hypertension crisis.

About this research paper

What this paper is about

Objective To evaluate the effects of intravenous diltiazem for aged patients with hypertension crisis. Methods Intravenous diltiazem was given to group A(n=30, SBP 192.4±17.2mmHg and DBP 110.6±8.8 mmHg) 10-20 mg, and intravenous nitroglycerin was given to group B(n=31, SBP 189.7±16.9 mmHg and DBP 112.8± 7.4 mmHg) 10 mg within 2 hours. The blood pressure (BP) was observed after 5 min, doses recorded and regulated according to BP, ECG, HR, SBP, DBP, HR×SBP and tolerance dosage. Results After treatment with diltiazem and nitroglycerin the BP of all patients decreased significantly(P0.01). More adverse events like headache(8 patients), dizziness, swelling, palpitation(6 patients) developed and 3 patients could not tolerate in group B. ST-T, in ECG improved in 2 groups but there was no statistical significance. None suffered from A-VB, severe low BP and heart failure. Conclusions The intravenous diltiazem is more effective and safer to treat aged patients with hypertension crisis.

Why it matters

A significance statement is not available in the OpenAlex record.

Key contribution

A contribution statement is not available in the OpenAlex record.

Method / approach

Method details are not available in the OpenAlex metadata.

Main findings

Findings are not separately available in the OpenAlex metadata.

Limitations

Limitations are not available in the OpenAlex metadata.

Applications

Application details are not available in the OpenAlex metadata.

Available abstract

Objective To evaluate the effects of intravenous diltiazem for aged patients with hypertension crisis. Methods Intravenous diltiazem was given to group A(n=30, SBP 192.4±17.2mmHg and DBP 110.6±8.8 mmHg) 10-20 mg, and intravenous nitroglycerin was given to group B(n=31, SBP 189.7±16.9 mmHg and DBP 112.8± 7.4 mmHg) 10 mg within 2 hours. The blood pressure (BP) was observed after 5 min, doses recorded and regulated according to BP, ECG, HR, SBP, DBP, HR×SBP and tolerance dosage. Results After treatment with diltiazem and nitroglycerin the BP of all patients decreased significantly(P0.01). More adverse events like headache(8 patients), dizziness, swelling, palpitation(6 patients) developed and 3 patients could not tolerate in group B. ST-T, in ECG improved in 2 groups but there was no statistical significance. None suffered from A-VB, severe low BP and heart failure. Conclusions The intravenous diltiazem is more effective and safer to treat aged patients with hypertension crisis.

Key concepts: Diltiazem, Medicine, Blood pressure, Adverse effect, Anesthesia, Cardiology, Internal medicine, Calcium

Related papers

Related paper 1Related paper 2Related paper 3
Back to paper searchBrowse research topicsOriginal source
The effects of intravenous diltiazem for aged patients with hypertension crisis — Research Paper | ScholarLens