Salmeterol Xinafoate and Fluticasone Propionate Powder with Montelukast Soudium in Treatment of Pre-school Children Asthma

Objective:To compare the effectiveness of Salmeterol Fluticasone Powder Inhalant combined with Montelukast and single Salmeterol Fluticasone powder inhalant.Method:80 cases with moderate intermittent asthma in preschool childen(aged 3-5)were randomly divided into two groups. The trial group with Salmeterol Fluticasone powder inhalant 50/100 μg(GlaxoSmithKline Co.)for each 12 h inhalation time,Montelukast 4mg (Hangzhou MSD)morning meal in a suit;the control group only used Salmeterol Fluticasone powder inhalant 50/100 μg(GlaxoSmithKline Co.)for each 12 h inhalation time. The two groups were gargle with warm water after treatment.After treatment,compared lung function and asthma control test score of two groups,and observed adverde reactiond. Result:After 3 months of treatment,the treatment group compared with the control group,in treatment group,PEFR value of the percentage of predicted value compared with the control group improved significantly( P 0.05),the clinical symptoms and the treatment group was significantly better than the control group( P 0.01).Conclusion:Salmeterol inhalation fluticasone and montelukast tablets pre - school children asthma combination therapy is more rapid improvement in clinical symptoms and lung function,can significantly improve the efficacy of the treatment of children with asthma.