Clinical effect of montelukast combined salmeterol and fluticasone propionate dry powder in children with moderate to severe asthma

Objective:To observe the effect of montelukast combined salmeterol and fluticasone propionate dry powder in children with moderate to severe asthma.Methods:38 patients of 4～14 years old with severe asthma in non-acute attack period were treated with Montelukast combined salmeterol and fluticasone propionate dry powder and 30 cases in the control group received salmeterol and fluticasone propionate dry powder.The total effective rate in the treatment group and control group was 92.1%and 70%respectively.Lung function in the two groups after 3 months in 1 second forced expiratory volume(FEV1)were significantly increased compared with that before treatment(P0.01).Conclusion:Montelukast combined salmeterol and fluticasone propionate dry powder inhalation therapy in children with asthma significantly improved asthma and easily accepted by the advantages of good bundle.