2015Xiandai shengwu yixue jinzhanRequires access

Efficacy of Montelukast Sodium and SALMETEROL Fluticasone Powder Inhalation on Childhood Bronchial Asthma

Liu Run-nin

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Abstract

Objective: To explore the efficacy and recurrence of Montelukast Sodium and SALMETEROL Fluticasone Powder Inhalation on childhood bronchial asthma. Methods: Selected 100 cases of children bronchial asthma from Sep,2011 to Dec, 2012 in our hospital,which were randomly divided into two groups: control group and study group, 50 cases in each.The control group were taken SALMETEROL Fluticasone Powder Inhalation for 6 months, while the study group were taken Montelukast Sodium and SALMETEROL Fluticasone Powder Inhalation. observed the recurrence and control of asthma.Results: Two groups of indices of pulmonary function were improved after drug treatment. The lung function of study group was obviously improved than control group by 3 months, 6 months,and 6months after discontinuation, the differences were statistically significant(P0.05); The clinical control rates have improved significantly in two groups,but only the study group had significant difference(P0.05). The clinical control rate of study group was higher than that of control group by 3 months, 6 months, and 6 months after discontinuation, and the recurrence rate was significantly lower than the control group by 6 months, and 6 months after discontinuation(P0.05), the differences were statistically significant(P0.05). Conclusions:Montelukast Sodium and SALMETEROL Fluticasone Powder Inhalation on childhood bronchial asthma have obvious curative effect and low recurrence rate than treated with SALMETEROL Fluticasone Powder Inhalation alone.

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Objective: To explore the efficacy and recurrence of Montelukast Sodium and SALMETEROL Fluticasone Powder Inhalation on childhood bronchial asthma. Methods: Selected 100 cases of children bronchial asthma from Sep,2011 to Dec, 2012 in our hospital,which were randomly divided into two groups: control group and study group, 50 cases in each.The control group were taken SALMETEROL Fluticasone Powder Inhalation for 6 months, while the study group were taken Montelukast Sodium and SALMETEROL Fluticasone Powder Inhalation. observed the recurrence and control of asthma.Results: Two groups of indices of pulmonary function were improved after drug treatment. The lung function of study group was obviously improved than control group by 3 months, 6 months,and 6months after discontinuation, the differences were statistically significant(P0.05); The clinical control rates have improved significantly in two groups,but only the study group had significant difference(P0.05). The clinical control rate of study group was higher than that of control group by 3 months, 6 months, and 6 months after discontinuation, and the recurrence rate was significantly lower than the control group by 6 months, and 6 months after discontinuation(P0.05), the differences were statistically significant(P0.05). Conclusions:Montelukast Sodium and SALMETEROL Fluticasone Powder Inhalation on childhood bronchial asthma have obvious curative effect and low recurrence rate than treated with SALMETEROL Fluticasone Powder Inhalation alone.

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Available abstract

Objective: To explore the efficacy and recurrence of Montelukast Sodium and SALMETEROL Fluticasone Powder Inhalation on childhood bronchial asthma. Methods: Selected 100 cases of children bronchial asthma from Sep,2011 to Dec, 2012 in our hospital,which were randomly divided into two groups: control group and study group, 50 cases in each.The control group were taken SALMETEROL Fluticasone Powder Inhalation for 6 months, while the study group were taken Montelukast Sodium and SALMETEROL Fluticasone Powder Inhalation. observed the recurrence and control of asthma.Results: Two groups of indices of pulmonary function were improved after drug treatment. The lung function of study group was obviously improved than control group by 3 months, 6 months,and 6months after discontinuation, the differences were statistically significant(P0.05); The clinical control rates have improved significantly in two groups,but only the study group had significant difference(P0.05). The clinical control rate of study group was higher than that of control group by 3 months, 6 months, and 6 months after discontinuation, and the recurrence rate was significantly lower than the control group by 6 months, and 6 months after discontinuation(P0.05), the differences were statistically significant(P0.05). Conclusions:Montelukast Sodium and SALMETEROL Fluticasone Powder Inhalation on childhood bronchial asthma have obvious curative effect and low recurrence rate than treated with SALMETEROL Fluticasone Powder Inhalation alone.

Key concepts: Salmeterol, Fluticasone, Inhalation, Medicine, Discontinuation, Montelukast, Asthma, Anesthesia

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