Clinical observation of seretide plus montelukast in treating cough variant asthma in children inhalation

Objective To observe the clinical effects of seretide(salmeterol /fluticasone propionate),seretide plus montelukast in treating cough variant asthma(CVA) in children inhalation.Methods 58 cases of children with CVA were randomly divided into two groups respectively treated with seretide or seretide plus montelukast for 3 months.The pulmonary function and clinical symptom before and after treatment were observed in the two groups.Results The overall response rate was 93.1% in the treatment group and 79.3% in the control group.There were statistically significant differences between two groups(P 0.05).The treatment group was obviously superior to the control group in the cough remission and cough disappearance time(P 0.05).The indicators of pulmonary function in the two groups had improved before and after treatment(P 0.05),and the improving pulmonary function in the treatment group was significantly better than that in the control group(P 0.05).Conclusion The improvement of clinical symptoms and pulmonary function appears more rapidly in treating CVA by seretide plus montelukast than by seretide only.