Distribution and drug resistance of pathogens causing infections in burn patients

OBJECTIVE To understand the species of pathogens causing infections in burn patients and their resistance to commonly used antibiotics so as to guide the clinical medication.METHODS A total of 390 patients with burn infections who were enrolled in hospital from Feb 2001 to Sep 2011 were selected for the wound culture,the drug susceptibility testing was performed.RESULTS Totally 546 strains of pathogens were isolated,including 352(64.47%) strains of gram-negative bacilli among which Pseudomonas aeruginosa,Escherichia coli,Acinetobacter baumannii,and Enterobacter cloacae were dominant,175(32.05%) strains of gram-positive cocci among which Staphylococcus aureus(12.45%) and Enterococcus(10.62%) were dominant,and 19(3.48%) strains of fungi among which Candida albicans(1.83%) was dominant;drug susceptibility testing showed that gram-positive bacteria were most resistant to the first generation of cephalosporins,the resistance to vancomycin was the lowest;gram-negative bacteria were most resistant to the first generation of cephalosporins,the resistance to imipenem was the lowest.CONCLUSION Gram-negative bacteria are dominant in the pathogens causing burn wound infections,as for the patients with severe burn infections,imipenem is recommended.