Distribution and drug resistance of pathogens in burn department of a hospital in Ningxia from 2011 to 2013

Objective To explore the distribution and drug susceptibility of pathogens causing infections of the patients in the burn department so as to guide reasonable use of antibiotics and control bacterial infection effectively.Methods To analyze retrospectively the distribution characteristic and drug resistant status of bacterial with positive result of bacterial culture in burn department from Jan 2011 to Dec 2013.Results A total of 2 587 strains of pathogens were isolated from the patients of burn department,there were 832(32.1%)strains of gram-negative bacteria,among which the top three isolated species were Enterobacter cloacae(E.cloacae),Acinetobacter baumannii(E.baumanni)and Escherichia coli(E.coli),accounting for 9.3%,6.4%,5.2% respectively.The drug susceptibility rates of the E.cloacaeto ampicillin,cefazolin,piperacillin,cefoxitin and compound sulfcmethoxazole were 62.9%,100.0%,37.5%,100.0%,98.3%,respectively.The drug resistance rate of A.baumannii to most antimicrobials were over60.0%.The drug susceptibility rates of the E.coli to ampicillin,amikacin,levofloxacin were 91.8%,4.1%,56.8%,respectively.There were 1 728(66.8%)strains of gram-positive bacteria,among which the highest isolated pathogens were Staphylococcus aureus(S.aureus)and Staphylococcus epidermidis(S.epidermidis),accounting for 21.5%,9.4%,respectively.The drug resistance rate of S.aureus to most antimicrobials were more than 70.0%.The drug resistance rate of S.epidermidis to most antimicrobial were more than 40.0%.There was 27(1.1%)strains of fungi,among which the main pathogens was Candidaalbicans.Conclusion There are a variety of infection in the patients of burn department,the main pathogens was Staphylococcus aureus,the drug resistance rates of the pathogens to the commonly used antibiotics in the burn department are high,and most strains shows multi-drug resistance.Therefore,it is necessary to strengthen the monitoring of the drug resistance and guide the use of antibiotics.