2011•Zhongguo zhongyiyao xinxi zazhiRequires access

Optimization of Extraction Conditions of Berberine in Rhizoma Coptidis with Orthogonal Test

QI Zhi-hua

Abstract

Objective To optimize the extraction conditions of Rhizoma Coptidis.Methods The extraction conditions were studied with orthogonal test L9(34) and comparison test,and the content of berberine was determined by HPLC as index.Results Frequency of extraction was remarkable factor in the test.Conclusion The optimum extraction technology for Rhizoma Coptidis was shattering to 10 meshes,backstreaming and boiling the materials for 3 times in 60% ethanol,the volume of which was 9 times,8 times,8 times the weight of herbal medicine,with 1 hours for each time.

About this research paper

What this paper is about

Why it matters

A significance statement is not available in the OpenAlex record.

Key contribution

A contribution statement is not available in the OpenAlex record.

Method / approach

Method details are not available in the OpenAlex metadata.

Main findings

Findings are not separately available in the OpenAlex metadata.

Limitations

Limitations are not available in the OpenAlex metadata.

Applications

Application details are not available in the OpenAlex metadata.

Available abstract

Key concepts: Berberine, Extraction (chemistry), Chromatography, Traditional medicine, Boiling, High-performance liquid chromatography, Chemistry, Medicine